Displaying 38 (all) recruiting clinical trials.
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A Phase 2 Study of Blinatumomab in Combination with Chemotherapy for Infants with Newly Diagnosed Acute Lymphoblastic Leukemia with Randomization of KMT2A-Rearranged Patients to Addition of Venetoclax
This phase II trial tests the addition of venetoclax and/or blinatumomab to usual chemotherapy for treating infants with newly diagnosed acute lymphoblastic leukemia (ALL ...Phase
Interventional
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A Phase II Trial Evaluating Chemotherapy followed by Response-Based Reduced Radiation Therapy for Patients with Central Nervous System Germinomas
This is a phase II study, testing if lowering the dose of standard radiotherapy (RT) after standard chemotherapy medicines (Carboplatin & Etoposide) works well with fewer ...
Phase
Interventional
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Novel Targeting of the Microenvironment to Decrease Metastatic Recurrence of High-Risk TNBC: A Randomized Phase II Study of Tetrathiomolybdate (TM) Plus Capecitabine in Patients with Breast Cancer at High Risk of Recurrence
Scientific Rationale for the study design: Copper depletion is designed to be a complement to standard therapy to overcome resistance mechanisms hence it would be ...Phase
Interventional
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A Phase 2 Double-blind Placebo-Controlled Study to Evaluate LY3537021 for the Treatment of Chemotherapy-Induced Nausea and Vomiting in Adult Participants With Malignant Disease
This is a Phase 2 study testing how safe and effective a medicine called LY3537021 is when added to standard anti-nausea treatment. LY3537021 is a ...
Phase
Interventional
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An Open-label Multi-center Global Phase II Clinical Study to Evaluate the Efficacy and Safety of HLX43 (Anti-PD-L1 ADC) in Subjects with Advanced Non-small Cell Lung Cancer (NSCLC)
This is a Phase 2 study testing different doses of a medicine called HLX43 for patients with advanced non-small cell lung cancer (NSCLC). HLX43 is ...
Phase
Interventional
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A Phase 2 Open-Label Study to Evaluate the Safety and Efficacy of Intravesical Instillation of TARA-002 in Adults with High-Grade Non-Muscle Invasive Bladder Cancer
Study TARA-002-101-Ph2 is an open-label Phase 2 study to investigate the safety and efficacy of TARA-002 administered intravesically in adults 18 years of age or ...Phase
Interventional
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TITLE: TRIPL: Thoracic Radiotherapy and Inhibition of PD-1 and LAG-3 for Locally Advanced Non-Small Cell Lung Cancer
This is a Phase II study testing a new treatment for people with locally advanced non-small cell lung cancer (LA-NSCLC). The goal of this study ...
Phase
Interventional
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A multicenter trial utilizing ctDNA Guided Triplet Boost for Patients following treatment on nivolumab and relatlimab in patients with metastatic melanoma
Multi-site trial utilizing ctDNA measurements to guide first-line therapy choice for patients with advanced or metastatic melanoma.Phase
Interventional
