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AAML1531 Risk-stratified Therapy for Acute Myeloid Leukemia in Down Syndrome
If you are the parent or guardian of a child diagnosed with acute myeloid leukemia (AML) also born with Down Syndrome (DS), your child may ...
Phase
Interventional
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A Phase III Double-Blind Trial for Surgically Resected Early Stage Non-Small Cell Lung Cancer: Crizotinib versus Placebo for Patients with Tumors Harboring the Anaplastic Lymphoma Kinase (ALK) Fusion Protein
The main goal of this phase III study is to evaluate whether adjuvant therapy with crizotinib (an ATP blocker of several tyrosine kinases) will result ...
Phase
Interventional
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A Randomized Phase III Study of Sublobar Resection (SR) versus Stereotactic Ablative Radiotherapy (SAbR) in High Risk Patients with Stage I Non-Small Cell Lung Cancer (NSCLC)
The main goal of this study is to determine if limited surgery or high dose precision radiation is better in patients who are at an ...
Phase
Interventional
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A Double Blind Placebo-Controlled Trial of Eflornithine and Sulindac to Prevent Recurrence of High Risk Adenomas and Second Primary Colorectal Cancers in Patients with Stage 0-III Colon or Rectal Cancer Phase III Preventing Adenomas of the Colon with Eflornithine and Sulindac (PACES)
If you have been diagnosed with colon or rectal cancer, you may qualify to participate in a study evaluating the combination of the drugs eflornithine ...
Phase
Interventional
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ARST1431: A Randomized Phase 3 Study of Vincristine Dactinomycin Cyclophosphamide (VAC) Alternating with Vincristine and Irinotecan (VI) Versus VAC/VI Plus Temsirolimus (TORI Torisel NSC# 683864 IND# 122782) in Patients with Intermediate Risk (IR) Rhabdomyosarcoma
If you or your child have been diagnosed with rhabdomyosarcoma (RMS) a type of cancer that occurs in the soft tissues of the body like ...Phase
Interventional
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Colorectal Cancer Metastatic MSI-High Immuno-Therapy (COMMIT) Study: A Randomized Phase III Study of mFOLFOX6/Bevacizumab Combination Chemotherapy with or without Atezolizumab or Atezolizumab Monotherapy in the First-Line Treatment of Patients with Micros
If you have been diagnosed with Microsatellite Instability-High (MSI-H) Metastatic Colorectal Cancer, you may qualify for this Phase 3 study. The main goal of this ...Phase
Interventional
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Randomized Trial of Standard Chemotherapy Alone or Combined with Atezolizumab as Adjuvant Therapy for Patients with Stage III Colon Cancer and Deficient DNA Mismatch Repair
If you have been diagnosed with colon cancer that was surgically removed but has spread to lymph nodes and is known as stage III colon ...Phase
Interventional
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A Randomized Phase II Trial of Radiation Therapy and Cisplatin Alone or in Combination with Intravenous Triapine in Women with Newly Diagnosed Bulky Stage IB2 Stage II IIIB or IVA Cancer of the Uterine Cervix or Stage II-IVA Vaginal Cancer
If you have been diagnosed with locally advanced cervical or vaginal cancer, you may qualify for this Phase II study evaluating the investigational drug triapine ...Phase
Interventional
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TAILOR RT: A RANDOMIZED TRIAL OF REGIONAL RADIOTHERAPY IN BIOMARKER LOW RISK NODE POSITIVE BREAST CANCER
The purpose of this study is to determine whether there is any benefit of regional radiotherapy and to compare good and bad effects of not ...Phase
Interventional
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PANOVA-3: Pivotal randomized open-label study of Tumor Treating Fields (TTFields 150kHz) concomitant with gemcitabine and nab-paclitaxel for front-line treatment of locally-advanced pancreatic adenocarcinoma
To test the efficacy and safety of gemcitabine and nab-paclitaxel, with or without TTFields, using the NovoTTF-100L(P) System as a front-line therapy for locally-advanced ...Phase
Interventional
