Randomized Controlled Pivotal Trial of Autologous Bone Marrow Mononuclear Cells Using the CardiAMP Cell Therapy system in Patients with Post Myocardial Infarction Heart Failure (CardiAMP Heart Failure Trial)

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Heart Failure
  • Age: Between 21 - 90 Years
  • Gender: Male or Female
  • Other Inclusion Criteria:
    1. Subjects with New York Heart Association (NYHA) Class II or III (mild to moderate symptoms of shortness of breath and/or fatigue)
    2. Subjects diagnosed with weakened heart muscle after a heart attack
    3. Subjects with reduced ejection fraction (20% to 40%) measured by by two dimensional echocardiogram (sound wave picture of the heart)
    4. Subjects who are on stable recommended treatment for heart failure and previous heart attack
    5. Provide written informed consent
    6. At screening, able to walk between 100 to 450 meters in 6 minutes

You may not be eligible for this study if the following are true:

    1. Subjects who are pregnant or breastfeeding
    2. Subjects who are organ transplant recipient
    3. Subjects who have a clinical history of cancer within 2 years
    4. History of Hepatitis B, Hepatitis C, and or HIV
    5. Subjects with a history of asthma or chronic obstructive pulmonary disease (COPD), or other conditions that could limit the ability to perform the 6 Minute Walk Distance Test
    6. Have a known, serious radiological contrast allergy
    7. Not a candidate for cardiac catheterization
    8. Planning to undergo coronary artery revascularization (stent or bypass operation)
    9. Be currently participating (or participated within the previous 30 days) in an investigational therapeutic or device trial or participated in the treatment arm of a gene or stem cell therapy trial within the previous 12 months
    10. Subjects who have a history of drug or alcohol abuse within the past 24 months

If you are registered as a volunteer, please log in to contact the study team/express interest in this study.

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