Site for WUH: Methotrexate and Cholesterol Transport Regulation: Impact of Treatment Regimen in Diabetes and Metabolic Syndrome
Are you eligible to participate in this study?
You may be eligible for this study if you meet the following criteria:
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Conditions: Diabetes And Metabolic Syndrome
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Age: Between 18 Year(s) - 80 Year(s)
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Gender: Male or Female
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Other Inclusion Criteria:
- Subjects documented post-myocardial infarction (MI)
- Subjects with history of type 2 diabetes or metabolic syndrome
- Subjects willing to participate as evidence by signing the study informed consent
You may not be eligible for this study if the following are true:
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- Subjects with prior history of chronic infectious disease, including tuberculosis, severe fungal disease, or known HIV positive
- Subjects with chronic hepatitis B or C infection
- Subjects with interstitial pneumonitis, bronchiectasis, or pulmonary fibrosis
- Prior history of non basal cell malignancy or myeloproliferative or lymphoproliferative disease
- Subjects who have history of alcohol abuse
- Women of child bearing potential, even if currently using contraception, and women intending to breastfeed
- Men who plan to father children during the study period or who are unwilling to use contraception
- Subjects with current indication for methotrexate therapy
- Subjects with chronic use of oral steroid therapy or other immunosuppressive or biologic response modifiers
- Subjects with known chronic pericardial effusion, pleural effusion, or ascites
- New York Heart Association class IV congestive heart failure
- Life expectancy of <3 years
If you are registered as a volunteer, please log in to contact the study team/express interest in this study.