Evaluation of HFCWO using The Vest System for Treatment of Non-Cystic Fibrosis Bronchiectasis in the home setting

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Bronchiectasis
  • Age: Between 18 - 80 Years
  • Gender: Male or Female
  • Other Inclusion Criteria:
    1. Subjects with radiological diagnosis of NCFBE based on high resolution chest CT scan
    2. Subjects with history of at least 2 acute exacerbations or hospitalization in the past 12 months
    3. Subjects who are clinically stable for more than 2 weeks
    4. Subjects are able to provide signed informed consent

You may not be eligible for this study if the following are true:

  • • Diagnosis of Cystic Fibrosis • History of bronchiectasis secondary to primary immunodeficiency
    1. Subjects with active pulmonary tuberculosis
    2. Subjects on active treatment of Non-Tuberculous Mycobacterium (NTM)
    3. Subjects who are currently on HFCWO treatment
    4. Subjects who are diagnosed comorbidity or medical indication that would prevent study completion
    5. Subjects with history of pneumothorax within past 6 months
    6. Subjects with history of hemoptysis requiring embolization within past 12 months
    7. Subjects inability to perform HFCWO therapy or OPEP therapy as directed
    8. Pregnancy or lactation
    9. Subjects with inability or unwillingness to complete study visits or provide follow-up data as required by the study protocol



If you are registered as a volunteer, please log in to contact the study team/express interest in this study.