Microbial and human biomarkers of thoracic disease after lung transplantation

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Microbial and human biomarkers of thoracic disease after lung transplantation

Brief description of study

The purpose of this study is to identify biological markers associated with lung inflammation and immune responsiveness in lung transplantation. The study will prospectively collect airway and blood samples on 200 subjects undergoing lung transplantation. The research staff will evaluate airway microbial signatures associated with local (lower airway) and systemic (blood) immune tone. This study may lead to a better understanding of post-transplant (after transplant) outcomes.

Clinical Study Identifier: s19-01723

Principal Investigator: Leopoldo N. Segal.

Other Investigators: Melissa B. Lesko, Marlena Habal, Jamie L. Bessich, Samaan Rafeq, Darya Rudym, Stephanie H. Chang, Sheik Mohammad Imran Sulaiman, Kenneth I Berger, Mandana Mahmoudi, Massimo Mangiola, Matthias C. Kugler, Luis F. Angel.

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