International Study of Comparative Health Effectiveness with Medical and Invasive Approaches

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Cardiac Ischemia
  • Age: Between None - None
  • Gender: Male or Female
  • Other Inclusion Criteria:
    • At least moderate ischemia on a stress test
    • Participant is willing to follow the requirements of the study, including adherence to the assigned strategy, medical therapy and follow-up visits

You may not be eligible for this study if the following are true:

    • Left ventricular ejection fraction < 35%
    • History of unprotected left main stenosis >50% on prior coronary computed tomography angiography (CCTA) or prior cardiac catheterization (if available)
    • Prior known coronary anatomy not suitable for either percutaneous coronary intervention (PCI) or Coronary Artery Bypass Graft Surgery (CABG)
    • History of non-compliance with medical therapy
    • New York Heart Association class III-IV heart failure
    • Canadian Cardiovascular Society Class III angina of recent onset, OR angina of any class with a rapidly progressive or accelerating pattern
    • Canadian Cardiovascular Society Class IV angina, including unprovoked rest angina
    • Severe valvular disease or valvular disease likely to require surgery or percutaneous valve replacement during the trial
    • Acute coronary syndrome (unstable angina) within the previous 2 months
    • Stroke within previous 6 months
    • Percutaneous coronary intervention (angioplasty) within the previous 12 months



If you are registered as a volunteer, please log in to contact the study team/express interest in this study.