A Multicenter Adaptive Randomized Blinded Controlled Trial of the Safety and Efficacy of Investigational Therapeutics for the Treatment of COVID-19 in Hospitalized Adults

Brief description of study

COVID-19 is a respiratory disease caused by a novel coronavirus (SARS-CoV-2) and causes substantial morbidity and mortality. There are no approved medicines to treat COVID-19. This research is to test an experimental medicine, remdesivir, in adult patients that are hospitalized with COVID-19. The drug has been tested before in humans with other diseases. This research is to see if it is safe and effective in treating patients with COVID-19. Participants will get either remdesivir or a placebo (aninactive medicine), along with the best standard of care for up to 10 days.

Clinical Study Identifier: s20-00286

ClinicalTrials.gov Identifier: NCT04280705

Principal Investigator: Mark J. Mulligan.

Other Investigators: Benjamin J Eckhardt, Ellie R. Carmody, Henry J. Neumann, Tania Kupferman, Joseph O Rahimian, Vinh P Pham, Mary Christine Olson, Sarah E. Hochman, Kerry L. Dierberg, Anand Viswanathan.

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