Clinical Research Studies

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

• Conditions:
  Coronavirus Infection, Unspecified Site
• Age: Between 18 - 110 Years
• Gender: Male or Female

• Other Inclusion Criteria:
  

  1. Subjects who are admitted to a hospital with symptoms suggestive of COVID-19 infection.
  2. Subjects (or legally authorized representatives) able to provide written informed consent prior to initiation of any study procedures
  3. Subjects who understand and agree to comply with planned study procedures.
  4. Subjects who agree to the collection of oropharyngeal (OP) swabs.
  5. Subjects =18 years of age at time of enrollment.
  6. Subjects who have laboratory-confirmed SARS-CoV-2 infection as determined by PCR or other commercial or public health assay in any specimen collected <72 hours prior to randomization
  7. Subjects with illness of any duration, and at least one of the following:
     • Radiographic infiltrates by imaging (chest x-ray, CT scan, etc.), OR
     • Clinical assessment (evidence of rales/crackles on exam) AND SpO2 = 94% on room air, OR
     • Requiring supplemental oxygen, OR
     • Requiring mechanical ventilation
  8. Women of childbearing potential must agree to either abstinence or use at least one primary form of contraception for the duration of the study
  9. Subjects agree to not participate in another clinical trial for the treatment of COVID-19 or SARS-CoV-2 through Day 29

  
  

You may not be eligible for this study if the following are true:

• 1. Subjects with ALT/AST >5 times the upper limit of normal.
  2. Subjects with estimated glomerular filtration rate (eGFR) < 50 or requiring dialysis.
  3. Subjects who are pregnant or breast feeding.
  4. Subjects who are anticipating transfer to another hospital which is not a study site within 72 hours
  5. Subjects allergic to any study medication.