Off label study to evaluate the efficacy of Hydroxychloroquine for pre-exposure prophylaxis (PrEP) to prevent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among Health Care Workers who are high Risk of Occupational Exposure to SARS-CoV-2

Brief description of study

The Pre-exposure Prophylaxis (PrEP) Study, single, open and off label intervention study. 350 participants will be assigned to group that takes HCQ or group that opts to not take study medication. Participants will be NYULH health care workers high risk of occupational exposure to SARS-CoV-2. Study timepoints will include Screening/Enrollment, 30 day, 60 day, and 90 day visits. Questionnaires, DBS, and blood samples will be collected in all timepoints.


Clinical Study Identifier: s20-00390
ClinicalTrials.gov Identifier: NCT04354870
Principal Investigator: Howard Belmont
Currently Recruiting

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