A Randomized Trial of Anticoagulation Strategies in COVID-19:PROTECT-COVID 19

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Covid-19
  • Age: Between 18 years - 120 years
  • Gender: Male or Female
  • Other Inclusion Criteria:
    1. Subjects who are hospitalized with diagnosis of COVID-19
    2. Subjects with D-dimer > 500ng/ml (hypercoagulability)

You may not be eligible for this study if the following are true:

    1. Subjects with indication for therapeutic anticoagulation
    2. Subjects with COVID related “high-risk” indication for therapeutic anticoagulation
      • Renal failure
      • D-dimer >10,000 ng/ml, markedly increasing D-dimer
    3. Had prior Heparin induced thrombocytopenia within 100 days
    4. Had a stroke within 30 days
    5. Had prior hemorrhagic stroke (ever)
    6. Had Gastrointestinal bleeding within the past 6 months.
    7. Subjects with platelet count <100,000
    8. Has anemia with a hemoglobin <9mg/dl
    9. Subjects with signs of active bleeding or other bleeding risks
    10. Subjects who are pregnant
    11. Subjects who have no capacity to consent themselves



If you are registered as a volunteer, please log in to contact the study team/express interest in this study.