Anticoagulation for Stroke Prevention and Recovery after ICH (ASPIRE)
Are you eligible to participate in this study?
You may be eligible for this study if you meet the following criteria:
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Conditions: Hemorrhagic Stroke
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Age: Between 18 Year(s) - 105 Year(s)
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Gender: Male or Female
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Other Inclusion Criteria:
- Participants with intracerebral hemorrhage
- Participants with non-valvular AF (defined as atrial fibrillation or atrial flutter), documented by electrocardiography or a physician-confirmed history of prior AF
- Able to provide written informed consent
- Able to comply with all study procedures and available for duration of the study
- For females of reproductive potential: use of highly effective contraception
You may not be eligible for this study if the following are true:
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- Participants with history of ICH before index event
- Those with zctive infective endocarditis
- Participants with lobar ICH with cerebral amyloid angiopathy
- Those using anticoagulant drugs or antiplatelet drugs
- Participants who have previous or planned left atrial appendage closure
- Has clinically significant bleeding diathesis
- Active hepatitis or hepatic insufficiency
- Anemia (hemoglobin <8 g/dL) or thrombocytopenia (<100 x 109/L) that is chronic in the judgment of the investigator
- Life expectancy <1 year
- Participants who are pregnant or breastfeeding
- Has known allergy to aspirin or apixaban
- Participants who are currently in another clinical trial
- Unwilling to discontinue prohibited medications
If you are registered as a volunteer, please log in to contact the study team/express interest in this study.