Surveillance and Treatment to Prevent Fetal Atrioventricular Block Likely to Occur Quickly

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Fetal Atrioventricular Block
  • Age: Between 18 - 50 Years
  • Gender: Female
  • Other Inclusion Criteria:
    1. Participants who are =18 years of age and provide written informed consent
    2. Those who state willingness to comply with all study procedures and availablity for the duration of the study
    3. Be <18 weeks pregnant at the time of enrollment
    4. Ability to take oral medication and be willing to adhere to the dexamethasone and IVIG protocols.
    5. Any positive titer of anti-Ro if a history of a previously affected child
    6. Ability to perform Doppler fetal heart rate and rhythm monitoring in the ambulatory setting
    7. Ability to send an audiotext message by cell phone

You may not be eligible for this study if the following are true:

    1. Multi-fetal pregnancy
    2. Known allergic reactions to components of IVIG, or dexamethasone or maternal IgA deficiency
    3. Fetal conduction system disease already present in the current pregnancy
    4. Mentally ill women
    5. Women prisoners
    6. Cognitively impaired women
    7. Treatment with >20 mg/prednisone q day or with any dose of fluorinated steroids

If you are registered as a volunteer, please log in to contact the study team/express interest in this study.