Assessment of glutamate neurotransmission brain bioenergetics and neuroinflammation in major depressive disorder using TSPO PET and MRI

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Major Depressive Disorder
  • Age: Between 18 Year(s) - 65 Year(s)
  • Gender: Male or Female
  • Other Inclusion Criteria:
    Healthy Controls:
    1. Does not meet criteria for any DSM-5 diagnosis
    2. Scores of lower than 1 for hs-CRP, a blood inflammation marker, at screening
    Major Depressive Disorder (MDD):
    1. Meet DSM-5 diagnostic cri

You may not be eligible for this study if the following are true:

    1. Suicidal ideation
    2. Pregnant women
    3. Known history of serious or unstable medical illness
    4. Obese individuals (BMI >= 30) and individuals with cardiovascular risk factors
    5. History of seizure disorder, b


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