Validation of OCT-based FUnctional diagnoSIs of corONary stenosis (FUSION)

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
  • Age: Between 18 - 120 Years
  • Gender: Male or Female
  • Other Inclusion Criteria:
    1. People who are =18 years and able to provide written informed consent
    2. People who are scheduled for clinically indicated coronary catheterization with the intent to perform physiologic assessment to guide physician clinical course (in lesions with visual % diameter stenosis 60-90%), if clinically indicated
    3. People who are undergoing invasive FFR with Adenosine (high-dose intra-coronary (IC) [200 µg for the left and or 100 µg for the right coronary artery] or 140 µg/kg/min for intravenous (IV)) used as hyperemic stimulus
    4. Clinical presentation with stable angina or unstable angina

You may not be eligible for this study if the following are true:

    1. Prior history of myocardial infarction (MI)
    2. Has ST Elevation Myocardial Infarction (STEMI)
    3. Has Culprit vessel of Non-ST Elevation Myocardial Infarction (NSTEMI)
    4. Prior history of coronary artery bypass grafting (CABG)
    5. Prior heart transplant
    6. Severe valvular heart disease
    7. Prior history of PCI with stent in target vessel, or target vessel involves in-stent restenosis.
    8. Target coronary vessel is supplied by major collaterals or is supplying major collaterals to a CTO (chronic total occlusion)
    9. CTO in the target vessel
    10. Presence of myocardial bridge (MB)
    11. Known renal insufficiency unless on dialysis
    12. Heart Failure NYHA Class III or IV
    13. Pregnant
    14. Active COVID-19 symptoms and/or a positive test result within the prior 2 months
    15. Participating in another clinical study of an investigational drug or device
    16. Severe diffuse disease observed in target vessel
    17. Target lesion involves Left Main coronary artery or ostial right coronary artery

If you are registered as a volunteer, please login to the dashboard to send referrals.

Contact the research team to learn more about this study.

By clicking "Contact Research Team", your contact information will be sent securely to the research staff associated with the study. You will also receive a copy of this email in your inbox, as well as other notifications to determine your participation status in the study.