A single-center observational study of the relationship between sleep synovial fluid cytokine profiles & outcomes of ACL reconstruction
Are you eligible to participate in this study?
You may be eligible for this study if you meet the following criteria:
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Conditions: Acute Acl Tear
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Age: Between 18 years - 100 years
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Gender: Male or Female
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Other Inclusion Criteria:
- Male or female,at least 18 years of age who provide written informed consent
- Undergoing primary ACL reconstruction with BPTB autograft for acute ACL tear, with or without concomitant meniscectomy
- Showing symptoms within 2 weeks of injury and undergoing reconstruction within 8 weeks of injury
You may not be eligible for this study if the following are true:
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- Breastfeeding or pregnant
- History of blood-borne diseases including HIV, HBV, HCV, HTLV, or syphilis
- Multiligamentous knee injury
- Concomitant meniscal repair, meniscal allograft transplantation, osteotomy, or repair of focal chondral defect
- Prior ipsilateral knee surgeries or injuries
- Primary sleep disorders including insomnia, sleep apnea, or restless legs syndrome
- Uncontrolled psychiatric disorders with sleep disturbance
- Night shift work
- Travel with time zone change within three weeks of surgery
- Systemic inflammatory disease
- Autoimmune disease
- Immunomodulatory drug use
- Chemotherapy within a year before surgery
- Intra-articular injection within 3 months before surgery
If you are registered as a volunteer, please log in to contact the study team/express interest in this study.