Clinical Research Studies

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

• Conditions:
  Opioid Use Disorder
• Age: Between 18 Year(s) - 65 Year(s)
• Gender: Male or Female

• Other Inclusion Criteria:
  

  1. Adult volunteer able to provide written informed consent in English
  2. Current CJS incarceration (residing in a controlled environment) with pending release date (within 6 months of randomization) OR community CJS-involvement defined as:
     • Current CJS incarceration (residing in a controlled environment) with pending release date (within 6 months of anticipated randomization)
     • ommunity-dwelling volunteers with current CJS-involvement. Current CJS-involvement is defined as either 1) release from any CJS incarceration or detention, or 2) under community supervision
  3. Current or history of moderate-to-severe opioid use disorder
  4. Not planning to move out of state or to new location within 6-months post-release
  5. Willing to accept either XR-B or XR-NTX assignment

  
  

You may not be eligible for this study if the following are true:

• 1. Medical or psychiatric disorders
  2. Pregnant, planning conception or breast-feeding
  3. Allergy, hypersensitivity or medical contraindication to either medication
  4. Chronic pain requiring opioid pain management
  5. On daily stable methadone or buprenorphine (SL-B) maintenance every day for past 30 days prior to incarceration or monthly XR-NTX or XR-BUP 30 days or longer prior to incarceration AND intending to remain on same form of methadone or buprenorphine or XR-NTX maintenance upon return to the community