A Phase 2 12-Week Adaptive Open Label Sequential Cohort Trial to Evaluate the Efficacy Safety Tolerability and Pharmacokinetics of PF06730512 Following Multiple Doses in Adult Subjects with Focal Segmental Glomerulosclerosis (FSGS)
Brief description of study
The purpose of this research study is to learn about the effects, overall safety, how well people can tolerate (tolerability) the study drug (PF-06730512), and to see how much drug is in the blood (pharmacokinetics), following intravenous administration every two weeks over 12 weeks. Intravenous administration means that the study drug is infused into one of the veins on the arm. The primary goal of this study is to obtain an early sign that the drug works. PF-06730512 is an investigational drug. An investigational drug is one that is currently not approved for sale in the United States or any other country. Investigational drugs administered in clinical studies are also commonly known as study drugs.
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