Post-Viral Autoantibodies in Patients with Cognitive Dysfunction and/or Postural Orthostatic Tachycardia Syndrome (POTS).

Brief description of study

The two study visits will be at the NYU School of Medicine or the first visit could be performed remotely. These visits will last about 1 hour each. During the first visit, you will answer a series of questions about you, your medical history, and your symptoms. At the second visit, you will have your blood drawn, processed, sent for viral testing and to be analyzed for autoantibodies, which are abnormal antibodies that attack organs and tissues in your own body. This second visit must be performed in-person at NYU. If you are eligible for the study, which includes being 18 years or older, not pregnant, and have developed cognitive dysfunction and/or POTS within 2 months after a viral infection, then you will complete the questionnaires in the first visit. Then we will collect your blood samples and send them to our research laboratories for analysis, viral testing, and overseas to an international clinical laboratory that can test for autoantibodies commonly found among patients with POTS and/or cognitive dysfunction. Please note that these are not commonly performed tests and have not been validated as a way to confirm or diagnose patients with POTS or autoimmunity. There is the possibility that the tests results are inaccurate and we have no way of confirming the results. There is no cost for participation in the study. If you agree to participate, you will not receive compensation for travel and time. We will also recruit patients without these symptoms in order to compare the results with participants who have these symptoms. If you like to hear more about this study or enroll, please contact one of our research coordinators by email at: POTSautoantibodies@nyulangone.org


Clinical Study Identifier: s21-00463
Principal Investigator: David C Lee.


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