A multicenter adaptive prospective randomized trial evaluating the efficacy and safety of antithrombotic strategies in patients with COVID-19 following hospital discharge (ACTIV-4C)

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Covid-19
  • Age: Between 18 years - 110 years
  • Gender: Male or Female
  • Other Inclusion Criteria:
    1. Participants who are PCR-positive COVID-19 infection
    2. Hospitalized for 48 or more hours
    3. Participants who will provide written consent form

You may not be eligible for this study if the following are true:

    1. Existing indication for anticoagulation, either therapeutic or prophylactic dose
    2. Contraindication to antithrombotic therapy
    3. Pregnant
    4. Prison inmate
    5. Life expectancy less than 90 days
    6. Unwilling or unable to provide informed consent / unwilling or unable to complete the study protocol
    7. Other criteria related to arm-specific appendices developed as adaptations to the trial



If you are registered as a volunteer, please log in to contact the study team/express interest in this study.