The Effect of Bone-void filler on Anterior Knee Pain Following ACL Reconstruction with Bone-Patellar Tendon Bone Autograft

Brief description of study

The purpose of this study is to evaluate the effect of and compare bone-void filler material on outcomes following anterior cruciate ligament (ACL) reconstruction with bone-patella-tendon-bone (BPTB) autograft. During ACL reconstruction surgery with BPTB, surgeons remove a portion of the patella (knee cap) and may fill in the missing bone using a bone-void filler. There are different kinds of bone-void fillers that are used by surgeons. However, while each material has its own benefits and risks, there is no goldstandard or preferred material among surgeons. This study will compare bone obtained from the BPTB graft harvest, and bone graft plus calcium phosphate cement, and bone graft plus demineralized bone matrix (DBM) to see if there is a difference in knee pain as well as knee function and subject quality of life after surgery.


Clinical Study Identifier: s20-00081
ClinicalTrials.gov Identifier: NCT04533880
Principal Investigator: Eric J Strauss.
Other Investigators: Guillem Gonzalez-Lomas, Laith M Jazrawi, Kirk A Campbell, Michael J Alaia, Alexander Ross Hoberman.


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