Unpacking the Importance of the Structural Injuries of MTBI

Brief description of study

This is a research study supported by a federal grant through the National Institutes of Health (NIH) to investigate new ways to identify and measure mild traumatic brain injury (MTBI) or concussion and the related brain changes. Concussion is a common injury and there is growing concern regarding what the long-term effects may be for some individuals. This research study uses new MRI (magnetic resonance imaging) techniques including advanced diffusion MRI which allows us to image brain tissue microstructure changes after injury. MRI has no radiation and is one of the only windows we have into the concussed brain. By studying patients who have sustained a concussion in the past 6 months, the researchers seek to better understand the recovery process after injury as well as understand what happens to individuals with persistent symptoms. The researchers hope to learn if new MRI scanning techniques can find distinct imaging findings that allow us to better evaluate patients with MTBI. The study involves brain MRI, neurocognitive exam, as well as a complete clinical assessment performed by physicians who are experts in concussion. These concussion experts will also make any needed clinical referrals/recommendations needed by patients.


Clinical Study Identifier: s20-01745


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