Understanding CSF Clearance in Aging and Alzheimer s Brain Through Dynamic Sodium MRI

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Early Stage Probable Alzheimer's Disease
  • Age: Between 65 - 120 Years
  • Gender: Male or Female
  • Other Inclusion Criteria:
    For normal aging subjects
    1. Age of =25 years.
    2. Have regular wake-sleep cycle.
    3. Able to undergo MRI
    4. willing to provide informed consent
    For sleep study subjects
    1. Age of =25 years
    2. Have regular wake-sleep cycle
    3. Able to undergo MRI
    4. Willing to provide informed consent
    5. Having sleep experience in MRI or in sleep lab
    6. Willing to have EEG in the MRI scanner
    For AD patients
    1. Age of 65-120 years
    2. Able to undergo MRI
    3. Willing to provide informed consent
    4. Clinically diagnosed probable AD at early stage

You may not be eligible for this study if the following are true:

  • For normal aging subjects
    1. Any known neurological disorders/symptoms
    2. Within 8 hours after coffee, stimulating tea, alcohol, or drug (excluding medications)
    3. Pregnant women
    For sleep study subjects
    1. Any known neurological disorders/symptoms
    2. Within 8 hours after coffee, stimulating tea, alcohol, or drug (excluding medications)
    3. Pregnant women
    4. Any known sleep disorders
    5. Can’t sleep in MRI or with EEG
    For AD patients
    1. Any known neurological disorders except AD
    2. Within 8 hours after coffee, tea, alcohol, or drug (except medications for AD)



If you are registered as a volunteer, please log in to contact the study team/express interest in this study.

Contact the research team to learn more about this study.

By clicking "Contact Research Team", your contact information will be sent securely to the research staff associated with the study. You will also receive a copy of this email in your inbox, as well as other notifications to determine your participation status in the study.