Controlled Study Comparing the Immune Response and Safety of a Research Yellow Fever Vaccine Candidate to a Licensed Yellow Fever Vaccine for Adults

Brief description of study

The NYU Langone Vaccine in Manhattan is taking part in a phase 2 yellow fever vaccine trial sponsored by Sanofi Pasteur comparing a research yellow fever vaccine to an FDA licensed vaccine. In this study, healthy volunteers will be randomly assigned to one of two groups where for every three participants, two will receive the research yellow fever vaccine and one will receive the FDA licensed yellow fever vaccine. The research yellow fever vaccine is a live-attenuated vaccine that was developed as an alternative to the current egg-based vaccine, which can be more difficult to manufacture. The goal of this study is to see if the newly developed yellow fever vaccine works just as well or better than the currently approved yellow fever vaccine. You will be asked to complete 9-10 visits over the next 5 years. There is no cost if you decide to take part in the study and you will receive compensation for travel and time.




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