PARAGLIDE-HF
Are you eligible to participate in this study?
You may be eligible for this study if you meet the following criteria:
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Conditions: Heart Failure
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Age: Between 40 - 125 Years
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Gender: Male or Female
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Other Inclusion Criteria:
- Participants must provide written informed consent
- Currently hospitalized for or within 30 days following discharge of an acute decompensated Heart failure with preserved ejection fraction (HFpEF) admission
- HFpEF with most recent left ventricular ejection fraction (LVEF) >40% (within past 3 months)
You may not be eligible for this study if the following are true:
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- Any clinical event within the 90 days prior to randomization that could have reduced the LVEF
- Currently taking Entresto™ (sacubitril/valsartan) or any prior use
- Probable alternative diagnoses that in the opinion of the investigator could account for the patient’s HF symptoms
- Isolated right HF in the absence of left-sided structural heart disease
- History of hypersensitivity (i.e. including angioedema), known or suspected contraindications, or intolerance to any of the study drugs including ARNIs (i.e. sacubitril/valsartan), and/or ARBs
- Participants with a known history of angioedema due to any etiology
If you are registered as a volunteer, please log in to contact the study team/express interest in this study.