CAreful Ventilation In ARDS The CAVIARDS Trial
Brief description of study
A basket trial design examines a single intervention in multiple disease populations . This basket trial consists of an identical 2-arm mechanical ventilation protocol implemented in two different study populations (COVID-19 and non-COVID-19 patients). As per a typical basket trial design, the operational structure of both CAVIARDS-19 and CAVIARDS-non substudies is shared (recruitment, procedures, data collection, analysis, management, etc.). Note that the protocol and all procedures are identical between the two substudies in this basket trial. The only differences between the two studies will be the randomization stratified by suspection of COVID-19, as clarified in Section 4.5.
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