Clinical Research Studies

The purpose of this research study is to compare the effectiveness of vaginal hyaluronic acid (HLA) to vaginal estrogen cream for the treatment of genitourinary syndrome of menopause (GSM). GSM is also known as vulvovaginal atrophy, urogenital atrophy, or atrophic vaginitis. It is a condition characterized by changes to the vaginal, vulvar, and urethral areas of post-menopausal women due to a low estrogen state.. Symptoms that result from these changes include vaginal dryness, burning, painful sexual intercourse, increased urinary frequency/urgency, and/or recurrent urinary tract infections. While vaginal estrogen cream has been the gold standard treatment for this condition for many years, not every women is able to use this medication, many wish to avoid hormonal therapy, and some women do not experience significant or any improvement from this treatment. Thus, the goal of this study is to study an alternative, non-hormonal medication, HLA.