A randomized single center study comparing hyaluronic acid to vaginal estrogen for treatment of genitourinary syndrome of menopause

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Genitourinary Syndrome Of Menopause
  • Age: Between 18 - 100 Years
  • Gender: Female
  • Other Inclusion Criteria:
    1. Postmenopausal status
    2. Symptoms of genitourinary syndrome of menopause (GSM)
    3. If age <65 years old and cervix still present, negative Pap smear with HPV co-test in the last 5 years or negative Pap smear without HPV co-test in the last 3 years
    4. Capable of giving informed consent
    5. Ambulatory
    6. Capable and willing to follow all study-relation procedures

You may not be eligible for this study if the following are true:

    1. Use of any HRT (systemic or local) or raloxifene within six weeks of proposed start date
    2. History of estrogen-sensitive tumor
    3. Undiagnosed vaginal bleeding in the past 12 months
    4. History of thromboembolic event
    5. Currently have or have had liver problem
    6. Bleeding disorder
    7. Impaired mental status
    8. Prior pelvic irradiation
    9. Active vaginal infection
    10. Any medical reason the investigator deems incompatible with treatment with vaginal estrogen



If you are registered as a volunteer, please log in to contact the study team/express interest in this study.