DISCOVER: A single-site double-blind placebo-controlled randomized mechanistic crossover trial to assess the influence of boDy weIght on aSpirin-triggered speCialized prO-resolVing mEdiatoRs

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DISCOVER: A single-site double-blind placebo-controlled randomized mechanistic crossover trial to assess the influence of boDy weIght on aSpirin-triggered speCialized prO-resolVing mEdiatoRs

Brief description of study

This study employs a placebo-controlled randomized cross-over design to investigate the impact of body weight and aspirin dose on levels of specialized pro-resolving lipid mediators in blood and neutrophils.

Clinical Study Identifier: s20-01884

ClinicalTrials.gov Identifier: NCT04697719

Principal Investigator: Sean P. Heffron.

Other Investigators: Hua Zhong, Leonardo Trasande.

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