DISCOVER: A single-site double-blind placebo-controlled randomized mechanistic crossover trial to assess the influence of boDy weIght on aSpirin-triggered speCialized prO-resolVing mEdiatoRs

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
  • Age: Between 40 Year(s) - 70 Year(s)
  • Gender: Male or Female
  • Other Inclusion Criteria:
    1. Age between 40 and 70 years without known atherosclerotic cardiovascular disease (ASCVD)

You may not be eligible for this study if the following are true:

    1. Atherosclerotic cardiovascular disease (ASCVD)
    2. Anti-platelet medication use in the past 7 days
    3. Aspirin intolerance or allergy
    4. Known bleeding or clotting disorder
    5. Chronic inflammatory or connective tissue disease
    6. Immunological deficiency
    7. Diabetes mellitus
    8. Prior gastric or bariatric surgery
    9. Active smoking
    10. Platelet count <100,000
    11. Use of omega-3 fatty acid supplementation
    12. Use of drugs or supplements known to inhibit COX-1/COX-2/lipoxygenases
    13. Corticosteroid use
    14. Recent initiation or change in dose of statin therapy
    15. Pregnancy

If you are registered as a volunteer, please log in to contact the study team/express interest in this study.

Contact the research team to learn more about this study.

By clicking "Contact Research Team", your contact information will be sent securely to the research staff associated with the study. You will also receive a copy of this email in your inbox, as well as other notifications to determine your participation status in the study.