Observational Study Assessing for Effect of CREON on Symptoms of Exocrine Pancreatic Insufficiency (EPI) in Patients with EPI due to Chronic Pancreatitis (CP)

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Chronic Pancreatitis
  • Age: Between 18 years - 99 years
  • Gender: Male or Female
  • Other Inclusion Criteria:
    1. Diagnosis of Chronic Pancreatitis
    2. Diagnosis of Exocrine pancreatic insufficiency (EPI)
    3. Pancreatic enzyme replacement therapy (PERT) naive subjects, to be initiated on CREON 72,000 LU/meal, and 36,000 LU/snack per treating physician recommendations, independently of this study
    4. Subjects must be able to understand and adhere to the study requirements, and must voluntarily provide informed consent
    5. Moderate to severe symptoms of EPI

You may not be eligible for this study if the following are true:

    1. Subjects with Pancreatic Exocrine Insufficiency Questionnaire Total symptom score (PEI-Q SS) <1.4
    2. Subjects must not have other gastrointestinal conditions which symptoms might impact the SS: cystic fibrosis, pancreatic cancer, pancreatic surgery, gastric bypass surgery, extensive bowel surgery, inflammatory bowel disease, celiac disease, irritable bowel syndrome
    3. Subjects must not have any planned pancreatic endotherapy or pancreatic surgery intervention within 3 months (± 1 month) following enrollment
    4. Subjects must not be participating or intending to participate in a concurrent interventional therapeutic trial

If you are registered as a volunteer, please log in to contact the study team/express interest in this study.