Clinical Research Studies

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

• Conditions:
  Coronary Artery Disease
• Age: Between 18 years - 100 years
• Gender: Female

• Other Inclusion Criteria:
  

  1. Signs and symptoms of suspected ischemia prompting referral for further evaluation by cardiac catheterization, or coronary angiogram or coronary CT angiogram within 5 years from consent
  2. Non-obstructive CAD defined as 0 to 49% diameter narrowing of a major epicardial coronary artery
  3. Willing to provide written informed consent

  
  

You may not be eligible for this study if the following are true:

• 1. History of noncompliance to medical therapy or follow-up
  2. History of non-ischemic dilated or hypertrophic cardiomyopathy
  3. Documented acute coronary syndrome within previous 30 days
  4. Left ventricular ejection fraction (LVEF) less than 40%, NYHA class III-IV, or hospitalization for heart failure with reduced ejection fraction (HFrEF) within 180 days
  5. Stroke within previous 180 days or intracranial hemorrhage at any time
  6. End-stage renal disease, on dialysis, or estimated glomerular filtration rate (eGFR) less than 30 ml/min.
  7. Severe valvular disease or likely to require surgery/TVAR within 3 yrs
  8. Life expectancy less than 3 years due to non-cardiovascular comorbidity
  9. Enrolled in a competing clinical trial.
  10. Prior intolerance to both an ACE-I and ARB
  11. If intolerant to a statin unless taking a PCSK9 as a statin replacement by their clinical provider
  12. Pregnant