A Randomized Double-blind Placebo-controlled Parallel-group Multicenter Study to Assess the Effect on Cognitive Decline and Safety of JNJ 63733657 an Anti tau Monoclonal Antibody in Participants with Prodromal Alzheimer s Disease

Brief description of study

The purpose of this study is to evaluate the safety and effectiveness of an experimental drug called JNJ-63733657 for treating subjects with Early Alzheimer’s disease, defined as prodromal and mild dementia due to Alzheimer’s disease. Early Alzheimer’s disease is the beginning stages of Alzheimer’s disease (AD) where the person has memory loss but remains independent or has some diminished daily function. An experimental drug is one that is being tested and is not approved by the United States Food and Drug Administration (FDA). Some subjects in this study may receive placebo instead of JNJ-63733657. A placebo is an inactive substance used to determine whether and how well the study drug works.


Clinical Study Identifier: s19-02012
ClinicalTrials.gov Identifier: NCT04619420


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