Evaluating Long COVID Patients with Persistent Respiratory Symptoms for Prothrombotic Immune Responses and Pulmonary Microvascular Thrombosis Using SPECT-CT Lung Perfusion Studies
Are you eligible to participate in this study?
You may be eligible for this study if you meet the following criteria:
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Conditions: Long Covid
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Age: Between 18 - 100 Years
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Gender: Male or Female
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Other Inclusion Criteria:
- Long COVID patients who meet the clinical case definition of post COVID-19 as determined by consensus recommendations by the World Health Organization and have persistent respiratory symptoms, which include shortness of breath, dyspnea on exertion, or hypoxia at rest or upon exertion, or
- Healthy control patients who have a prior history of SARS-CoV-2 infection, but with resolution of symptoms and no characteristics of Long COVID
- Patients must be willing and able to provide informed consent
You may not be eligible for this study if the following are true:
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- Patients with a current or past history of pulmonary thromboembolism
- Significant parenchymal lung disease, such as pulmonary fibrosis, ground glass opacities, or bullous lung disease, which may otherwise explain the presence of ongoing respiratory symptoms among Long COVID patients
- Contraindication to CT angiography or SPECT-CT lung perfusion scan, which includes pregnancy, breastfeeding, chronic kidney disease, or having a history of allergy to intravenous contrast or nuclear medicine tracer compounds
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