Clinical Research Studies

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

• Conditions:
  Obsessive-compulsive Disorder
  Major Depressive Disorder
• Age: Between 18 Year(s) - 55 Year(s)
• Gender: Male or Female

• Other Inclusion Criteria:
  

  For MDD or OCD Subject Group:

  1. Meet DSM-5 criteria for a diagnosis of OCD or MDD with at least mild disorder severity
  2. Fluent in English

  For Healthy Control Subject Group:

  1. Free from any current or past DSM-5 psychiatric diagnosis
  2. Fluent in English

  
  

You may not be eligible for this study if the following are true:

• For OCD or MDD Subject Group:

  1. Current severe alcohol or substance use disorder per DSM-5 criteria; lifetime history of schizophrenia spectrum, bipolar, or autism spectrum disorders
  2. Current use of a psychiatric medication to treat OCD or MDD that is not at a stable dose (constant for at least six weeks)
  3. MRI contraindications (claustrophobia, metal in body)
  4. A medical condition that may hinder, or increase risk associated with, participation
  5. A urine toxicology positive for drugs other than cannabis or prescribed medications taken as directed
  6. A positive urine pregnancy test.

  For Healthy Control Group:

  1. Use of any psychiatric medication
  2. Evidence that first-degree biological relative has OCD or MDD
  3. MRI contraindications (claustrophobia, metal in body)
  4. A medical condition that may hinder, or increase risk associated with, participation or
  5. A urine toxicology positive for drugs other than cannabis or prescribed medications taken as directed
  6. A positive urine pregnancy test.