Heterogeneity in OCD and Depression

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Obsessive-compulsive Disorder
    Major Depressive Disorder
  • Age: Between 18 - 55 Years
  • Gender: Male or Female
  • Other Inclusion Criteria:
    1. Meet DSM-5 criteria for a diagnosis of OCD or MDD with at least mild disorder severity
    2. Fluent in English

You may not be eligible for this study if the following are true:

  • OCD or MDD Subject Group:
    1. Current severe alcohol or substance use disorder per DSM-5 criteria; lifetime history of schizophrenia spectrum, bipolar, or autism spectrum disorders
    2. Current use of psychiatric medication to treat OCD or MDD other than a stable dose (constant for at least six weeks) of either a serotonin reuptake inhibitor or bupropion, which are allowed
    3. MRI contraindications (claustrophobia, metal in body)
    4. A medical condition that may hinder, or increase risk associated with, participation
    5. A urine toxicology positive for drugs other than cannabis or prescribed medications taken as directed
    6. A positive urine pregnancy test.



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