A Prospective Randomized Controlled Trial to Assess the Management of Moderate Aortic Stenosis by Clinical Surveillance or Transcatheter Aortic Valve Replacement : The PROGRESS Trial

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A Prospective Randomized Controlled Trial to Assess the Management of Moderate Aortic Stenosis by Clinical Surveillance or Transcatheter Aortic Valve Replacement : The PROGRESS Trial

Brief description of study

This is a randomized 1:1 trial in which subjects will receive transcatheter aortic valve replacement (TAVR) with the SAPIEN 3/SAPIEN 3 Ultra transcatheter heart valve or clinical surveillance and will stratified by the site.

Clinical Study Identifier: s21-01143

ClinicalTrials.gov Identifier: NCT04889872

Principal Investigator: Richard K Schwartz.

Other Investigators: Giorgio A Medranda, Scott L Schubach, Sunil Abrol, Khaled F Salhab.

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