Clinical Research Studies

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

• Conditions:
  Pulmonary Mycobacterium Avium Complex Disease
• Age: Between 18 Year(s) - 99 Year(s)
• Gender: Male or Female

• Other Inclusion Criteria:
  

  1. At least 2 positive Mycobacterium Avium Complex(MAC) sputum cultures in the last 12 months with at least one AFB positive sputum obtained within 16 weeks prior to randomization
  2. Meet American Thoracic Society (ATS)/ Infectious Disease Society of America (IDSA) 2007 pulmonary clinical disease criteria
  3. Diagnosis of Bronchiectasis and/or bronchiectatic findings evident on chest CT report
  4. Ability to provide informed consent

  
  

You may not be eligible for this study if the following are true:

• 1. Any patient who is unwilling or unable to provide consent or to comply with this protocol
  2. Cavitary Nontuberculous mycobacterial (NTM) disease
  3. Patients who are currently taking or within the prior 6 months received any of the following: bedaquiline, or any component of ATS/IDSA multi-drug recommended therapy (macrolide, ethambutol, rifampin) for MAC treatment
  4. Patients who are currently taking or within the prior 3 months received continuous hypertonic saline, as defined by at least 4 days/week
  5. Diagnosis of HIV
  6. Diagnosis of Cystic fibrosis
  7. Active pulmonary tuberculosis, fungal, or nocardial disease requiring treatment at screening
  8. Current use of chronic systemic corticosteroids at doses of 15 mg/day for more than 3 months
  9. Prior lung or other solid organ transplant