A Telehealth tDCS Approach to Decrease Cannabis Use: Towards Reducing Multiple Sclerosis Disability

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Multiple Sclerosis
    Cannabis Use Disorder
  • Age: Between 21 - 65 Years
  • Gender: Female
  • Other Inclusion Criteria:
    1. Seeking treatment to reduce or discontinue current cannabis use (smoke/vape/ingest)
    2. Current Cannabis Use Disorder per DSM-V (MINI for DSM-V)
    3. K10 score 10-35, inclusive (mild to high moderate distress)
    4. Definite MS diagnosis, relapsing remitting (RRMS) subtype
    5. PDDS score 0 - 7 (mild to moderate neurological disability, established to be able to complete procedures)
    6. All medications stable for 1 or more months prior to enrollment and throughout the trial
    7. Ability to understand the informed consent process and provide consent to participate in the study
    8. Stable and continuous access to internet service, email (WiFi "hotspot"to be provided if needed)
    9. Ability to use mobile devices
    10. Fluent in English language (due to outcomes validated in English versions only)
    11. WRAT-4 score equal or more than 85

You may not be eligible for this study if the following are true:

    1. MS clinical relapse or use of high dose of steroids in the past month
    2. Patients under medical marijuana use prescribed by a clinician
    3. Alcohol, tobacco, or substance use disorder other than cannabis
    4. Primary neurologic, psychiatric or other medical disorder other than MS (entry MD screening)
    5. Currently meets DSM-V criteria for moderate or severe substance use disorder in the past 6 months for any psychoactive substance
    6. Meets DSM-V criteria for current panic disorder, obsessive-compulsive disorder, post-traumatic stress syndrome, bipolar affective disorder, schizophrenia, dissociate disorders, and any other psychotic disorder or organic mental disorder
    7. Current suicidal ideation or deemed to be of potential risk of self-injury
    8. History of traumatic brain injury
    9. Seizure disorder or recent (<5 years) seizure history
    10. Metal implants in the head or neck
    11. Enrolled in group or individual therapy for substance use disorder concurrent to intervention
    12. Any skin disorder or skin sensitive area near stimulation locations
    13. Pregnant or breastfeeding



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