A Randomized Double-Blind Placebo-Controlled Phase 3 Study of ISIS 678354 Administered Subcutaneously to Patients with Severe Hypertriglyceridemia

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Hypertrygliceridemia
  • Age: Between 18 - 99 Years
  • Gender: Male or Female
  • Other Inclusion Criteria:
    1. Participants who have severe high triglycerides
    2. Participants should be on standard of care (SOC) lipid-lowering medications per local guidelines

You may not be eligible for this study if the following are true:

    1. Genetically Confirmed Diagnosis of Familial Chylomicronemia Syndrome
    2. Prior use of investigational med or volseran
    3. Cancer within 5 years of Screen
    4. Active infection with HIV, Hepatitis B or Hepatitis C
    5. Pregnant or breast feeding
    6. Bleeding disorder
    7. Liver disorder
    8. Kidney disorder



If you are registered as a volunteer, please log in to contact the study team/express interest in this study.

Contact the research team to learn more about this study.

By clicking "Contact Research Team", your contact information will be sent securely to the research staff associated with the study. You will also receive a copy of this email in your inbox, as well as other notifications to determine your participation status in the study.