Gut Kidney Axis in Enteric Hyperoxaluria

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Gut Kidney Axis in Enteric Hyperoxaluria

Brief description of study

The purpose of this research study is to study the effects of enteric hyperoxaluria (EH) when they are given a pre-prepared diet. EH is a condition in which a person’s body does not properly absorb fat in the gut, which leads to higher than normal levels of oxalate in your urine, a natural substance found in the human body and in many foods. EH can develop as a result of inflammatory bowel disease or gastric bypass surgery. High levels of oxalate in the urine can cause kidney stones and other, sometimes serious kidney conditions. People who have EH should follow a special diet to avoid foods that contain oxalate and fat, and they must take supplements (for example, calcium salts) to help the body get rid of extra oxalate.

Clinical Study Identifier: s21-01274

ClinicalTrials.gov Identifier: NCT05124886

Principal Investigator: Lama Nazzal.

Other Investigator: David S. Goldfarb.

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