Psoriatic Response and Onset: Genes Radiology Environment Skin and Synovium)

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Psoriatic Response and Onset: Genes Radiology Environment Skin and Synovium)

Brief description of study

This is a longitudinal, observational cohort study to aimed to understand the clinical and biologic underpinnings of psoriasis and psoriatic arthritis development and severity. To this aim, we will collectThis will contain information related to each participant’s age, gender, race, past and present medical history, family history and social history, medications, and patient reported outcomes, and disease state. Additionally, biosamples such as blood, stool, skin biopsies, skin swabs, synovial fluid, synovial biopsies, saliva/buccal swabs, and hair follicle samples will be obtained as appropriate for each patient. Ultrasounds and brain MRIs will also be offered to a subset of patients. While a core set of samples and questions will be required, additional samples and procedures will be optional. Patients will be followed up to 4 times per year.

Clinical Study Identifier: s22-00484

Principal Investigator: Jose U Scher.

Other Investigators: Avrom S Caplan, Michael Toprover, Shruti Naik, Soumya M Reddy, Harshita Kukreja, Mariana Lazar, Alisa N Femia, Rebecca Barbara Blank, Laith M Jazrawi, Rebecca Haberman, Andrea L. Neimann, Sergei B Koralov, Souptik Barua, Kelly V Ruggles.

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