Mechanisms of Peripheral Vascular Disease

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Mechanisms of Peripheral Vascular Disease

Brief description of study

The proposed study will enable the use of human tissue samples and outcome data by basic and clinical investigators for research into the biology, causes, prevention and therapy of patients with documented peripheral arterial vascular disease secondary to atherosclerosis. The collection of paired information will provide important clinically relevant findings that will add to the growing understanding of the natural history of plaque formation in the arteries of the periphery and will enable to decipher the molecular mechanisms in this pathology. We will prospectively collect both tissue to study the mechanism of the natural history of PAD. We will also collect relevant clinical and medical information on these subjects and continue to collect follow-up information on the surgical patients using their medical records in order to follow their outcome.

Clinical Study Identifier: s21-01318

Principal Investigator: Bhama Ramkhelawon.

Other Investigators: Omri B. Ayalon, Thomas Maldonado, Katherine Teter, Jacques H. Hacquebord, Glenn R Jacobowitz, Karan Garg, Patrick J Lamparello, Caron B Rockman, Todd L. Berland, Neal S Cayne, Mikel Sadek.

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