The use of cannabidiol (CBD) in pain reduction for knee osteoarthritis. A Double-Blind Randomized Control Study

Brief description of study

The purpose of this study is to see if cannabidiol (CBD) orally dissolving tablets (ODTs) can lessen pain needed in people with knee osteoarthritis. CBD comes from the cannabis plant and is non-psychoactive (i.e. does not produce a ‘high’ or altered mental state) as compared to tetrahydrocannabinol (THC), another compound found in cannabis. Researchers are studying different forms of CBD for potential use in treating pain, inflammation, and illnesses. One form of CBD is Food and Drug Administration (FDA) approved for treating severe types of epilepsy that affect children. In this study, the CBD ODT is considered an investigational drug because it is not Food and Drug Administration (FDA) approved for osteoarthritis.


Clinical Study Identifier: s21-00334
ClinicalTrials.gov Identifier: NCT05020028
Principal Investigator: Michael J Alaia.


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