Multiparametric Mapping of Knee Joint with Magnetic Resonance Fingerprinting

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Osteoarthritis
  • Age: Between 18 years - 75 years
  • Gender: Male or Female
  • Other Inclusion Criteria:
    Healthy volunteers (Aim 2)
    1. Subject willing and able to comply with the MRF-MRI protocol
    2. No pain/inflammation based on phone screening
    Healthy volunteers and early Knee OA patients (Aim 3)
    1. Radiographic evidence of early knee OA patients (KL-1,2) according to ACR criteria
    2. Subject willing and able to comply with the MRF-MRI protocol

You may not be eligible for this study if the following are true:

  • Healthy volunteers (Aim2)
    1. No history of diagnosed OA, RA and knee surgery
    2. Pregnancy and all female subjects of childbearing who have doubts about their pregnancy
    3. Contraindications to 3T whole body MRI scanners
    Healthy volunteers and early Knee OA patients (Aim 3)
    1. Patients with advanced OA ( KL>2) in both knees and any joint disease other than knee OA
    2. Diabetes mellitus, cancer, heart failure, chronic infectious diseases , previous knee injury
    3. Contraindications to 3T whole body MRI scanners
    4. Pregnancy and all female subjects of childbearing who have doubts about their pregnancy



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