Clinical Research Studies

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

• Conditions:
  Rheumatoid Arthritis
• Age: Between 18 Year(s) - 100 Year(s)
• Gender: Male or Female

• Other Inclusion Criteria:
  

  1. Have a diagnosis of adult-onset Rheumatoid Arthritis (RA)
  2. If RA symptom onset is <6 months, are rheumatoid factor or anticitrullinated antibody positive
  3. Be clinically suitable, in the investigator's opinion, to receive a targeted therapy
  4. Have moderately to severely active Rheumatoid Arthritis (RA)
  5. Have had an IR or intolerance to at least 1 DMARD (synthetic or biologic)
  6. Have at least one of the following 4 characteristics:
     • Documented evidence of a VTE prior to this study
     • Age =60 years
     • BMI =30 kg/m2
     • Age 50 to <60 years AND BMI 25 to <30 kg/m2
  7. Abstinent or use 1 highly effective method of contraception
  8. Provide written informed consent

  
  

You may not be eligible for this study if the following are true:

• 1. Have any contraindications to a TNF inhibitor
  2. Are pregnant or breastfeeding
  3. Have a history of VTE (DVT/PE) within 12 weeks prior to randomization
  4. Have active primary or recurrent malignant disease or have been in remission from clinically significant malignancy for <5 years prior to randomization
  5. Have active herpes zoster
  6. Have a clinically serious infection or have any other active or recent infection that, in the opinion of the investigator, would pose an unacceptable risk to the participant
  7. Have a history or presence of any illness that, in the opinion of the investigator, could pose an unacceptable risk to the participant
  8. Have had household contact with a person with active tuberculosis (TB) and did not receive appropriate and documented prophylaxis for TB
  9. Have evidence of active TB or untreated/inadequately/inappropriately treated for latent TB