APOL1 Long-term Kidney Transplantation Outcomes Network

Brief description of study

The purpose of this study is to test kidney donors and kidney transplant recipients for apolipoprotein L1 gene (called APOL1) variants (or forms of the gene) and to see how these may affect them. Genes control the traits that you inherit from your family such as your eye color or blood type. Variation or changes in genes can also put some people at risk for developing certain diseases. Previous research has shown that variation in the APOL1 gene can put people at higher risk for kidney disease. African Americans, Afro-Caribbeans, Hispanic Blacks and Africans are more likely to have the APOL1 gene variants that cause kidney disease than are others. The purpose of this study is to test kidney donors for APOL1 gene variants and to see how the gene may impact people who donate a kidney and those who receive a kidney transplant.

Clinical Study Identifier: s20-01054
Principal Investigator: Vasishta Tatapudi.

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