Cardiometabolic Biomarker improvements associated with reduction in air pollution exposure via home air filtration.

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Cardiovascular Disease
  • Age: Between 18 - 100 Years
  • Gender: Male or Female
  • Other Inclusion Criteria:
    1. Participant and members of household are reported to be non-smokers
    2. Participant understands/speaks English or Spanish
    3. Participant can understand study procedures and give informed consent
    4. Participant has stable hypertension: no medication changes in prior 30 days, systolic BP <160 mm Hg and either =130 mm Hg without antihypertensive medications, or diagnosis of hypertension in medical records
    5. Able to measure home blood pressure twice daily
    6. Able to participate in video conference for home equipment setup
    7. Able to visit clinic for blood draws before and after the study period
    8. Do not intend to sleep anywhere outside of primary bedroom for more than 48 consecutive hours or a total of 7 days during the study period
    9. Ability to lift, or access to assistance with lifting, 20 lb to set up Portable Air Cleaner(PAC) in bedroom

You may not be eligible for this study if the following are true:

    1. Participants who are unable to provide a minimum of at least one blood pressure measurement per day
    2. Participants with average home blood pressure monitor readings of a systolic blood pressure (SBP) >160 mmHg over any 10-day period during the study. This will be considered evidence of uncontrolled hypertension and will require study termination
    3. Participants with known coronary artery disease
    4. Participants with known systemic inflammatory conditions (such as rheumatoid arthritis, inflammatory bowel disease, cancer)
    5. Participants currently taking any anti-inflammatory medications or medications that target inflammatory cytokines
    6. Pregnancy



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