A single-center cross-sectional observational pilot study of organophosphate pesticide exposure and semen quality in young men

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Male Subfertility
  • Age: Between 22 - 29 Years
  • Gender: Male
  • Other Inclusion Criteria:
    1. Healthy male
    2. English-speaking
    3. Provision of appropriate consent
    4. Willingness and ability to follow study protocol

You may not be eligible for this study if the following are true:

    1. Prior diagnosis with any of the following:
      • Klinefelter syndrome
      • cystic fibrosis
      • azoospermia, or absence of motile sperm in semen
      • cryptorchidism, or undescended testis
      • varicocele
      • testicular cancer
      • orchitis, painful infection of the testes from any cause (e.g. mumps, gonorrhea, chlamydia)
      • sickle cell disease
      • chronic kidney disease or kidney failure
      • HIV
    2. Diagnosis of any of the following within the past 90 days:
      • urethritis, or uncomfortable infection in the urethra, from any cause (e.g. chlamydia, gonorrhea, genital mycoplasma infection, or trichomonas)
      • active syphilis
      • active HPV infection (genital warts)
      • active genital herpes infection
    3. Current use of the any of the following medications and/or others (if notified by prescribing physician of fertility side-effect) known to transiently affect fertility:
      • spironolactone
      • ketoconazole
      • cimetidine
      • methotrexate
      • vinblastine
      • bleomycin
      • etoposide
    4. Treatment with either of the following (e.g. as part of cancer treatment regimen):
      • pelvic radiation
      • chemotherapy with agent(s) known have lasting effects on fertility
    5. Prior vasectomy
    6. Use of any of the following, prescribed or otherwise, within the past 90 days:
      • Anabolic steroids
      • Growth hormone
      • Protein or creatine supplements
      • Glucosamine
      • Testosterone
      • Estrogen
      • Hormone blockers



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