A Study to Evaluate Lumasiran in Adults with Recurrent Calcium Oxalate Kidney Stone Disease and Elevated Urinary Oxalate Levels

Brief description of study

The purpose of this study is to learn how lumasiran impacts adult patients with recurrent calcium oxalate kidney stone disease. This study will look at how much oxalate is in your urine, the number of kidney stones you have and the quality of life will be examined. The study will also investigate the potential side effects of lumasiran and how the body responds to it. This study will last about 15 months and will involve about 10 visits. While in this study you will be asked to do the following: Physical Examination, vital signs, take study drug, ECG, blood and urine tests, 24h urine collections, electronic diaries, quality of life questionnaires, and answer questions about your medications and daily life.


Clinical Study Identifier: s22-00130
ClinicalTrials.gov Identifier: NCT05161936


If you are registered as a volunteer, please log in to contact the study team/express interest in this study.